HCG Pregnyl FAQ

1)What is HCG?
HCG stands for Human Chorionic Gonadotropin.

2)Where does HCG come from?
It is extracted from the urine of pregnant women.

3)Is HCG a scheduled medication?
No, its similar to clomid and Liquidex as far as US laws go. However you would need a prescription to purchase legally in the US.

4)What is HCG normally used for?
It is used to help females get pregnant, and can be used to stimulate testosterone production in males.

5)How does HCG work?
HCG mimics LH (leutenizing hormone). The presence of LH causes the Leydig cells in the gonads to produce testosterone . This effect also restores the size of the testes rather quickly if they were suppressed from a cycle.

6)What should HCG be used for?
HCG is commonly used by bodybuilders on either very heavy or very long cycles, when the HPTA gets severely suppressed. Although HCG can be used in almost any cycle, the benefits are most pronounced on heavy/long ones.

7)How do you take it?
You can take it IM or Sub-q.

8)Can I use HCG only for PCT?
No you shouldn't. It is better than nothing, but clomid or Nolva are far better plans. Since HCG mimics lh, your body wont begin producing its own lh, as it sees no need to because test levels are high. You stop the HCG, your balls stop making test until your body begins producing adequate levels of its own lh, and that may take a while if you don't use clomid or Nolvadex to stimulate lh production. The use of clomid or Nolvadex should also be continued at least 2 weeks after HCG is discontinued to avoid the HCG causing problems.


Bacteriostatic Water Injection Starter Pack
9)Can I use HCG during cycle and when?
Yes you can, imo to best benefit from HCG is to run it by the last 3-4 weeks of your steroid cycle. Do not run HCG if your getting signs of gyno, HCG will make it worst, so be careful.

10)How much HCG is needed during cycle and/or PCT?
For PCT a minimum of 10,000iu's HCG is needed. When you have a proper PCT planned with a SERM and an AI, and you want to run HCG during the last 4 weeks of your cycle, then you might only need 5,000iu's.
An anti-estrogen (Nolva, etc.) is to be used with HCG during your last 4 weeks of cycle.

11)What dose do you run HCG at?
HCG is best dosed at 500iu and/or 1000iu, more than that can cause too much aromatization, and some people wont react to less than 500iu. So during the last 4 weeks of a cycle, you shoot 500iu of HCG twice a week or 1000iu once a week. For PCT, 500iu ed or 1000iu eod.

12)Can HCG be used w/out Steroids to boost test production above baseline?
Yes. It is not recommended however. Continued use of HCG will desensitize the Leydig cells to lh, meaning once you stop using the HCG as an artificial lh, you will crash bad. The natural lh production once restored by using Nolvadex or clomid, may not be as effective as it once was. To boost natural test above baseline, Anastrozole, Nolvadex and clomid are better choices.


13)How long does HCG boost testosterone for?
HCG can boost testosterone for up to 5 days following the last dose, although the drugs half-life is very short, and its no longer active at that point.

14)Can HCG cause gyno?
Yes. estrogen is elevated by two ways from HCG use. Primarily from the sharp rise in testosterone , which allows more testosterone to aromatize to estrogen. Secondly HCG can cause a small amount of estrogen to be produced which is not from the result of aromatizing, and this is the reason that a combination of an anti aromatize such as Liquidex/Arimidex/Letrozole and a estrogen receptor blocker such as Nolvadex are ideally used. The Nolvadex may also offer some additional benefit to help avoid a negative estrogen feedback to the HPTA during HCG therapy, which would otherwise slightly lessen the effectiveness of the therapy.

15)How does HCG come packaged?
You get 2 vials or amps, 1 has the powdered HCG in it, and the other has a diluent in it (solvent). The diluent is typically bacteriostatic water, or sterile water w/ .09% sodium chloride. ***ending on the brand and version, the package commonly comes w/ enough diluent to make concentrations ranging from 250-10,000iu per ml.

If your package is 5000iu, and you add 1ml diluent, you have 5000iu per ml.
If you add 5ml diluent, you final mix is then 1000iu per ml.
If you add 10ml diluent, then 500iu per ml and so on.

This is simple math, and you don't want to screw it up, know what dose you are taking!

If your package doesn't include enough diluent to make the concentration you want, you have 2 options to make it easy to accurately measure your doses.

1-buy some insulin syringes, U-100 type. On the graduated markings, the 100iu mark is equal to 1ml, the 50iu is .5ml etc. THIS DOES NOT MEAN IF YOU FILL IT TO THE 100IU MARK THAT YOU ARE TAKING 100IU OF HCG! Iu's are not a measurement of volume or weight, they are a measure of effectiveness for a desired response from specific drugs/compounds. Every compound is different. These are insulin syringes, and they are made for insulin-not HCG. Insulin is the same iu concentration per ml everytime if its u100 type), HCG is not. Imagine if you made your HCG 10,000iu per ml. if you fill the insulin syringe up to 100iu mark, you now have 10,000iu in there! Not good. You must understand this.
So if you had 5000iu per ml, and wanted to take a 500iu shot, you would inject 10iu on the insulin syringe scale.

2-buy some bacteriostatic water off the internet, its easily found. Simply add more to dilute it to the desired concentration. Making lower concentrations are easier and more accurately dosed. Then it can accurately be measured w/ a regular syringe.

Mix the two together, they dissolve very easily. HCG can be very unstable and to make sure to not shake it and let it foam.... Be careful when reconstituting it . Be gentle and run the bacteriostatic  water down the side of the vial not allowing to foam up... Keep things sterile folks. Unused HCG can be refrigerated and is ok to use within 30 days after the initial mixing.

Remember: Store HCG at controlled room temperature (59F to 86F)(15C to 30C). After reconstituting store in refrigerator (36F to 46F) (2C to 8C).

Absorption
A detectable rise in HCG is seen in 2 h; peak levels are reached in 6 h and remain at this level for 36 h.

Elimination
HCG levels begin to decline at 48?h and approach baseline at 72 h.

Superdrol Cycling and PCT

Superdrol (SD) is marketed as a 'pro-hormone' (PH) in the post-ban era of pro-hormones. Following the ban of most pro-hormonal substances in the States, including the likes of 1-test, 1-AD, 4-AD, M1T, etc, Designer Supplements designed this 'pro-hormone' based on the steroid Masteron, with an additional methyl group attached to the 17th carbon position. It is described as a cross between anavar and masteron, with the virtual inability for aromatisation to estrogen. It is highly anabolic (400-800% more so than methyl-test) and a lot less androgenic (~20% of methyl-test). Superdrol has hence been given the name Methasteron.

Despite being marketed as a supplement available legally and deemed another 'pro-hormone' or 'pro-steroid' by many, there is nothing very 'pro' about Superdrol. In reality, Superdrol is a designer steroid, and that is what the reader must primarily understand. It is methylated, so will cause stress on the liver, and it is an anabolic/androgenic steroid, thus it has the potential to give side effects normally seen with such anabolic androgenic steroid (AAS) use. It will shut your natural testosterone production down, and PCT (post-cycle therapy) is not only recommended, but frankly required.

It should also be noted that due to the steroidal nature of Superdrol, those under the age of 21 should not consider the use of Superdrol, which could be detrimental in a number of ways.

Cycling Superdrol
Superdrol is sold in 10mg capsules. For those who have not used Superdrol before, it may be a good idea to start off on 10mg as a single dose each day (ed) for at least the first few days/week. Those who have used Superdrol before, or those who are in the range of 200lbs+ or have more experience with other pro-hormones/AAS should most likely want to start with 20mg ed. Dosages should be split where possible, 10mg in the morning, 10mg 12hrs later. Most users report that when running for longer than 3 weeks, the gains seem to cease in the 4th week. This has led to many people thinking that 3 week cycles of SD are the best option in terms of gains and sides and this also is beneficial due to the harsh nature of Superdrol on lipid values (see Side Effects of Superdrol). A good cycle is 20mg ed for 3 weeks, with a 2-3 week PCT. Others have found success employing a 2 week on, 1 week off using a Selective Estrogen Receptor Modulator (SERM; e.g. Nolvadex) or Aromatase Inhibitor (AI; e.g. Rebound XT) during the week off.

Example of a Superdrol Cycle - (values given are every day - ed)

3-5 days prior to cycle (supplement loading):

    1000mg Milk Thistle
    1200mg RYR
    60mg CoQ10
    3g Taurine

Week 1:

    20mg Superdrol, split doses
    Supplement stack*

Week 2:

    20mg Superdrol, split doses
    Supplement stack*

Week 3:

    20mg Superdrol, split doses
    Supplement stack*

Post Cycle Therapy (PCT)

Either:

Rebound XT/ATD PCT week 1:

    75mg Rebound XT (3 caps 1 in morning, 2 in evening taken with 10g of fat ideally)
    Supplement Stack*

Rebound XT/ATD PCT week 2:

    50mg Rebound XT (1 cap in morning, 1 in evening, with 10g fat)

Rebound XT/ATD PCT week 3:

    25mg Rebound XT (1 cap in evening, with fat)

Or:

Nolvadex (Tamoxifen) PCT Day 1:

    60mg Tamoxifen (taken all at once when convenient)
    Supplement stack*

Nolvadex (Tamoxifen) PCT Days 2-11:

    40mg Tamoxifen (taken all at once when convenient)
    Supplement stack* (up to days 5-7)

Nolvadex (Tamoxifen) PCT Days 12-21:

    20mg Tamoxifen

Optional extra: Add Tribulus throughout PCT.

*Supplement stack:

    1000mg Milk Thistle
    1200mg RYR
    60mg CoQ10
    5g Taurine

Water intake should be high throughout the cycle.

Generally time on + PCT should equal time off, so one should ideally wait 6 weeks after PCT finishes before starting a new cycle of SD. SD can be stacked with other 'pro-hormones,' but I do not recommend stacking with those that are methylated as this will put too much unnecessary strain on the liver, even with Milk Thistle supplementation.

Lighter individuals (<170lbs) and those less adventurous may want to consider starting off on 10mg ed for the first 3-7 days to assess how they react to it, and maybe increasing to 20mg ed from the second week onwards. Those that don't respond well after 2 weeks to 20mg ed may also wish to consider going up to 30mg ed, but sides can be a lot worse at this dosage in many. People may also want to consider running it for 4 weeks, and although the above is an example cycle I would recommend, a 4-week cycle would be fine; however I would not recommend anything longer than 4 weeks, due to lipid issues and diminishing returns/gains ceasing. The reason I suggest 3 weeks is many people see very little in the way of gains in the fourth week, and it is often unnecessary to go to the fourth week bearing in mind the side effects associated with SD (which can be cumulative).

While strength gains may appear alarmingly rapid, they do not come with a proportional increase in strength of connective tissue. As such, strict form and a level headed approach to training should be maintained, to reduce the likelihood of injury.

The Long-Term Use of Melanotan II for Tanning

How to use MT-II long term and how do to dose it?

There’s no medical evidence on that question, but Melanotan II has been used by very many people for many years now.

Melanotan II works by stimulating the alpha-melanocyte receptor, which promotes formation of melanin in response to sun exposure. When a substantial amount of MT-II has been taken within recent “memory” of the skin cells, an individual tans as if he were a genetically darker type.

Some find MT-II unsuitable for them because of development of moles, or because of uneven skin darkening. But for most it works very well with no problems, including when used long term.

A possible additional side effect is greater tendency to developing an erection, typically beginning several hours after taking the drug. Depending on the individual, dosing may need to be at least 1 mg for this to occur. I’d recommend against exceeding 2 mg at a time. For those specifically seeking this effect, bremalanotide (PT-141) would be another option. It’s reported to share MT-II’s pro-erectile effect, but with no effect on tanning.

Melanotan II has an initial loading phase, and – if desired – a maintenance phase after that. Or, its effect can be allowed to slowly wear off over a period of months, and loading can be repeated.

Usually, 10-30 mg total use is required during the loading phase, with paler individuals requiring more than relatively darker individuals. It’s best to start with very low dosage, such as only 0.25 mg per day, and then work up if desired. Many can tolerate 2 mg/day, but it’s possible that risk increases with such use, and it usually should not be necessary to load up that fast. Even 0.5 mg/day will allow loading with 30 mg in only two months, or 1.0 mg/day will allow that much loading in just 30 days.

To maintain the same tanning ability, ongoing per-year usage after this needs to be about 2-3 times the loading dosage, as an estimate. So for example if you needed 30 mg of loading to get the result you want, to maintain it you might need about 60-90 mg total Melanotan II over the course of the year. You’d already have injected 30 mg of that, so there would be 30-60 mg (typically three to six vials) remaining to inject over the next 11 months.

You could be very precise and figure this as 2.72 – 5.45 mg/month or 0.09 – 0.18 mg/day. But there’s no need to do that. Instead, it would be fine to figure it as a vial per 2-4 months. Once starting on a vial, it could be injected at an amount such as 0.5 mg/day until the vial is finished.

This is easier than having to inject it at all the time, and gives equivalent results.

The frequency of starting maintenance vials can be varied according to personal judgment of effect. There’s no problem with underestimating, or even with going a year or more without maintenance, because it’s always easy to catch back up.

Of course, sun is still required to get a tan. MT-II facilitates tanning, but does not directly cause it.