Monday, September 23, 2013

GP Oxan - Brand Version Steroid Oxandrolone

GP Oxan is the trademark name of the anabolic steroid Oxandrolone. Introduced in the US in 1964, Anavar is considered a Class I steroid. It is taken orally and has few known side Oxandrolone effects, binding well with the androgen receptor when taken in sufficient dosage.

Compared to other anabolic steroids available in the market GP Oxan is mildly anabolic, only slightly androgenic, and is not very toxic. It is also mild on the body's Hypothalamic-Testicular-Pituitary-Axis (HPTA) and does not aromatize or convert to estrogen a major problem for stronger anabolic steroids, which causes unwanted breast tissue to form (man boobs), called gynecomastia. As with any anabolic steroid however, high dosage of Anavar can reduce the production of luteinizing hormone (LH), halting the stimulation of Leydig cells in testicles to produce testosterone, and therefore can cause the testes to shrink or to atrophy. High dosages of Anavar (about 40-50mg) require Post Cycle Therapy (PCT) to stabilize protein catabolism and normalize the body's testosterone secretion. Anavar is also very popular because of its fat burning capability. Called a "fat-burning steroid," GP Oxan (Anavar) is said to reduce abdominal and visceral fat for those with the low to normal natural testosterone range.

Doctors usually prescribe Anavar for halting wasting related to AIDS and recovering involuntary weight loss to promote the regrowth of muscles. The drug Oxandrolone has also been used in treating cases of Osteoporosis in the past, showing partially successful results. Due to bad publicity in the abuse of the steroid however, Searle Laboratories (now Pfizer, Inc.) discontinued the sale of oxandrolone, but was later picked up by Bio-Technology General Corporation (now Savient Pharmaceuticals, Inc.), released in 1995 under the trademark name Oxandrin. The Food and Drug Administration (FDA) approved Oxandrolone for orphan drug status in treating weight loss caused by HIV, Turner's syndrome, and alcoholic hepatitis. Oxandrolone has also showed positive results in treating hereditary angioedema and anemia. In a study of the effect of Oxandrolone on burnt victims, those treated with Oxandrolone were found to have improved body composition, reduce hospital stay time, and preserved muscle mass.

Because GP Oxan is a mild steroid, it may require a higher dosage compared to stronger steroids. It is not without side effects however. Those thinking of upping their dosage for this drug just because it is comparably mild should think twice. Some studies show that there is a link between the prolonged use of Anavar and liver toxicity, similar to the effects of 17-alkylated steroids. Even in lesser dosages, some users have reported side effects such as nausea, bloating, itching (hives), gastro-intestinal problems, depression, skin rash, diarrhea, yellowing of the skin or eyes, unusual bleeding, swelling, and unusually colored stools. In rare cases, serious or even fatal liver problems can occur, as well as the development of heart disease. Regular laboratory testing is highly recommended when taking this drug, to closely monitor the liver and to ensure that low density lipoprotein (LDL; also called the 'bad cholesterol') has not increased.
For bodybuilders, normal dose for a first time Anavar user is considered to be at 10-30 mg's per day. However, 10 mg may be sufficient for someone who has never taken anabolic steroids beforehand. Higher dosages may lead to androgen receptor damage, HPTA suppression, and liver damage.

Sunday, September 15, 2013

Nandrolone PhenylPropionate (NPP)

NPP was never really all that popular simply because of availability issues. Many of the pharmacy grade NPP products range between 25mg-50mg/ml and are extremely expensive. Naturally, this limited its use among the bodybuilding crowd.

The recent increase in popularity of NPP can be attributed to the introduction of GP Phenyl 100 by Geneza Pharmaceuticals.

With NPP, you can bypass all that dead time.
19-Nortestosterone based drugs are known to shutdown HPTA very easily - think Trenbolone. Most bodybuilders will use Tren for around 6 weeks at the beginning of a cycle. NPP should be used in a similar manner.

Here's an example of a balanced cycle consisting of NPP

W1-6: Dbol
W1-6: NPP
W1-8: Test Prop

It is a good idea to run Test 2 weeks past the NPP, however; NPP can be used as a stand-alone.

Earlier, I compared NPP to Tren. They are similar in some ways but Tren is much more androgenic and stronger in general.

NPP shares some of the same sides associated with Deca (they are after all the same base compound). It should be noted that most of the sides that come with Deca are a result of its long ester. Decanoate ester is very hard to control and Nandrolone side effects are not easily countered like Testosterone related sides (Tamoxifen, Anastrozole, finasteride)

Overall, Nandrolone is a milder compound than Testosterone and is better mg for mg (but that's a matter of opinion)

Nandrolone PhenylProp should be injected at least every 3 days. A typical dose is 350mg-700mg a week for 5-8 weeks.

It stacks very well with Winstrol, Dbol, Test, EQ, Anavar

It does not stack well with Tren and especially Anadrol

Here are some good cycle suggestions:

Fast Acting Classic Test/Deca/Dbol cycle:

W1-6: Dbol 30mg ED
W1-6: NPP 150mg EOD
W1-8: Test Prop 150mg EOD

Highly Anabolic cycles

W1-6: NPP: 200mg E3D
W1-8: Anavar: 30mg ED

W1-6: NPP: 200mg E3D
W1-8: Winny: 50mg ED

A good First cycle:

W1-6: NPP: 150mg E3D
W1-4: Dbol: 25mg ED
(W5-8: Anavar: 30mg ED - optional)

NPP in a typical cycle

W1-10: EQ 400mg a week
W1-9: Test Cyp 600mg a week
W1-8: NPP 200mg E3D
W10-13: Test Prop 150mg EOD

Nandrolone got a very bad rap with many bodybuilders; there is no reason to use Nandrolone Decanoate if NPP available aside from year-round juicer using it for joint pain. Nandrolone is a tremendous bodybuilding drug that can take your physique to a whole different level but many people shy away from it because of what they have heard or experienced with Deca.

Tuesday, September 3, 2013

Why Athletes and Bodybuilders Use Clenbuterol

Why Athletes and Bodybuilders Use Clenbuterol

Clenbuterol is a decongestant and bronchodilator prescribed to those suffering from chronic breathing disorders, particularly asthma, to make breathing easier. It is available in salt form as Clenbuterol hydrochloride, as well as in 20mcg tablets, in syrup, and in injectable form. Clenbuterol belongs to the broad group of sympathomimetic drugs, affecting the sympathetic nervous system in various ways, mediated by the distribution of adrenoceptors.

Other uses of Clenbuterol
Clenbuterol is a 2 adrenergic agonist with some similarities to ephedrine a sympathomimetic amine used as an appetite suppressant, stimulant, decongestant, concentration aid, and treatment for hypotension related to anesthesia but with more potent and longer-lasting effect as stimulant and as a thermogenic drug. Clenbuterol causes an increase in CNS stimulation, aerobic capacity, oxygen transportation, and blood Clenbuterolpressure. It also increases the rate at with protein and fat is used up in the body and also helps slow down the storage of glycogen. Because of these effects, Clenbuterol is commonly used as a relaxant for smooth muscles, as well as an aid for weight loss. It is prescribed in dosages from 20-60 micrograms a day; a dose of more than 150 mg is not recommended.

Clenbuterol as a slimming aid
While Clenbuterol is approved for use in many countries as a broncholidator for asthma patients, the drug has been used as a weight loss drug or slimming aid. There are physical trainers who recommend Clenbuterol as a primary solution for achieving low body fat and better-looking cuts. In fact, it has become popular among bodybuilders and athletes.

How does it work?
Primarily a bronchodilator, Clenbuterol stimulates Beta-2 receptors, working selectively on the Beta-2-andrenergic receptors. Since it has minimal Beta-1 stimulating capability, Clenbuterol reduces airway obstruction without too much cardiovascular effect, making it a useful breathing aid for asthma patients. When Clenbuterol stimulates the Beta Receptors, it increases the body's temperature and heat production in the Mitochondria, thereby increasing the body's metabolic rate and decreasing a person's appetite. Beta-2 agonists increase lypolysis or fat loss and stimulate fat cells, making it an attractive slimming aid. Unfortunately, Beta-2 agents such as Clenbuterol can decrease insulin sensitivity and may cause high blood sugar or hyperglycemic reactions. Clenbuterol is an effective repartitioning agent, which is most often used in athletic circles. It increases the ratio of Fat Free Mass (FFM) to Fat Mass, by decreasing fat and possibly increasing FFM (3). It has a biphastic elimination and is thus reduced in the body in two different stages. Since it is a central nervous system stimulant, it acts like adrenaline and shares many of the side effects of other CNS stimulants like ephedrine. Side effects of Clenbuterol may include palpitations, tremor, restlessness, headache, insomnia, increased perspiration, and muscle spasms.

How Clenbuterol is used by athletes
Athletes usually use Clenbuterol after steroid treatment to balance the catabolic phase and obtain maximum muscle mass and strength. Clenbuterol can burn fat even without dieting because it slightly increases the body's temperature. This magnifies the effect of amdrogenic/anabolic steroids, thus some bodybuilders take these simultaneously. Clenbuterol is not approved by the FDA for medical use or as a fat loss supplement.